Anti-Cardiolipin IgG/IgM is an ELISA test system for the quantitative measurement of IgG and IgM class autoantibodies against cardiolipin in human serum or plasma. This product is intended for professional in diagnostic use only.
INTENDED PURPOSE
Antiphospholipid syndrome (APS, Hughes Syndrome) is a systemic autoimmune disease that causes thromboses, recurrent miscarriage or stillbirths, and stroke. Clinical symptoms are accompanied by specific autoantibodies in blood, which bind to phospholipids like cardiolipin, or phospholipid-binding proteins like beta-2-glycoprotein Autoantibodies against proteins of the coagulation cascade, e.g. prothrombin or annexin V may also be found patients with APS with otherwise negative phospholipid antibody results. In primary APS autoantibodies against phospholipids appear independently, while in secondary APS phospholipid antibodies are detected in conjunction with other autoimmune diseases, such as lupus erythematosus, rheumatoid arthritis, or Sjögren’s syndrome.
